Perfused Liver Utilisation Study
Chief Investigators: Professor Peter Friend and Dr Simon Knight
Primary sponsor: NIHR Invention for Innovation (i4i)
Funder: NIHR Invention for Innovation Challenge Awards
NHSBT Research Theme: Organ Donation and Transplantation
Perfused Liver Utilisation Study. Utilisation of normothermic machine preservation in extended criteria livers - a national threshold-crossing study.
To assess whether normothermic machine preservation (NMP) can increase the availability of livers for transplantation without compromising the outcome.
Threshold-crossing design with prospectively-defined efficacy threshold comparing the impact of NMP versus standard static cold storage on functional utilisation of high-risk livers offered for transplant in the UK.