REAL
Red cell transfusion in Acute Myeloid Leukaemia
Chief investigator: Dr Simon Stanworth
Primary sponsor: NHSBT
Funder: NHSBT Trust Fund Grant
NHSBT Research Theme: Patient Blood Management
Summary
A feasibility trial comparing restrictive versus liberal red cell transfusion strategies in adult patients with acute myeloid leukaemia receiving intensive chemotherapy.
Study hypothesis
It is feasible to achieve adherence when randomising patients to one of two haemoglobin thresholds and maintaining haemoglobin concentrations between either 71-80 g/L or 91-100 g/L.
Study design
A cross-over randomised controlled feasibility trial.