About us


About the Clinical Biotechnology Centre

The Clinical Biotechnology Centre was opened in April 1999. Our aim is to be the preferred provider of quality-assured DNA and protein-based therapeutics for healthcare, academic and commercial customers seeking to establish the safety and efficacy of innovative cellular and molecular therapies.

We manufacture small scale batches of GMP-grade plasmids. These are small fragments of DNA, used to carry a gene of interest into human cells. Each batch is characteristically unique and tailored to the specific requirements of each customer.

Over the past decade, we have been proud to support numerous high profile clinical trials, treating patients around the world with a broad range of infectious, malignant or inherited disorders.

We were thrilled to be awarded Leading Gene Therapy Products Manufacturer in the UK (2016), and Best Clinical Biotechnology Research Facility in the UK (2017).

Our milestones

1999 The centre opened
2000 The centre became fully operational
2001

First recombinant monoclonal antibody released for clinical trial

First plasmid DNA released for clinical trial
2002

Multiple humanised monoclonal antibody trials started

Production of 30-40 bespoke patient specific plasmid DNA vaccinations started
2004 First publicly-funded facility to be receive MHRA Manufacturing Authorisation
2008 Successful MHRA re-inspection, with licence extended to include importation of Investigational Medicinal Products
2010

Collaborator on £1.2million EME NIHR Grant

Successful MHRA re-inspection
2011 Strategic partnership with UCL Gene Therapy Consortium
2015 Successful MHRA re-inspection
2016 Awarded Leading Gene Therapy Products Manufacturer in the UK
2017 Awarded Best Clinical Biotechnology Research Facility in the UK Concept design completed for new facility at NHSBT, Filton

Get in touch

Call us on:

01934 880 150

07471 147 804

Email us at:

enqcbc@nhsbt.nhs.uk



You may also be interested in