About us
About the Clinical Biotechnology Centre
The Clinical Biotechnology Centre was opened in April 1999. Our aim is to be the preferred provider of quality-assured DNA and protein-based therapeutics for healthcare, academic and commercial customers seeking to establish the safety and efficacy of innovative cellular and molecular therapies.
We manufacture small scale batches of GMP-grade plasmids. These are small fragments of DNA, used to carry a gene of interest into human cells. Each batch is characteristically unique and tailored to the specific requirements of each customer.
Over the past decade, we have been proud to support numerous high profile clinical trials, treating patients around the world with a broad range of infectious, malignant or inherited disorders.
We were thrilled to be awarded Leading Gene Therapy Products Manufacturer in the UK (2016), and Best Clinical Biotechnology Research Facility in the UK (2017).
Our milestones
| 1999 | The centre opened |
| 2000 | The centre became fully operational |
| 2001 |
First recombinant monoclonal antibody released for clinical trial First plasmid DNA released for clinical trial |
| 2002 |
Multiple humanised monoclonal antibody trials started Production of 30-40 bespoke patient specific plasmid DNA vaccinations started |
| 2004 | First publicly-funded facility to be receive MHRA Manufacturing Authorisation |
| 2008 | Successful MHRA re-inspection, with licence extended to include importation of Investigational Medicinal Products |
| 2010 |
Collaborator on £1.2million EME NIHR Grant Successful MHRA re-inspection |
| 2011 | Strategic partnership with UCL Gene Therapy Consortium |
| 2015 | Successful MHRA re-inspection |
| 2016 | Awarded Leading Gene Therapy Products Manufacturer in the UK |
| 2017 | Awarded Best Clinical Biotechnology Research Facility in the UK Concept design completed for new facility at NHSBT, Filton |