Cellular and Molecular Therapies


Accelerating access to innovative therapies

Novel cellular and molecular therapies offer the promise of new treatments and potential cures for many diseases and disorders, and NHS Blood and Transplant is uniquely positioned to support the exciting developments that are taking place in this field.

Our experience in the processing and storage of stem cells for transplant and the manufacture of clinical grade advanced cellular and molecular therapies, combined with our strong links to clinicians and hospitals, means we can help bring new and ground-breaking treatments to the bedside.

GMP Plasmid and Viral Vector Manufacture

Our Clinical Biotechnology Centre (CBC) manufactures GMP-grade plasmids and viral vectors, supporting clinical trials. We also provide quality control and batch release testing services.

Find out more

GMP cell manufacture

We have four cell therapy facilities licensed to manufacture advanced therapy medicinal products. We provide a tailored process development and GMP manufacturing service for companies and academic groups developing cellular therapeutics for use in clinical trials.

Find out more

Stem Cell Immunotherapies for blood and bone marrow transplantation

We provide a comprehensive range of laboratory services supporting around 2,000 stem cell transplants a year from 5 laboratories across the country.

Find out more

ATMP storage and distribution

We support the supply of commissioned CAR-T cell therapies and ATMPs for clinical trial through receipt, storage and issue to the hospital.

Find out more

Who we help - Nitya's Story

Nitya was the first patient to receive CAR T cell therapy at the University of Bristol and Weston NHS Foundation Trust. CMT are supporting the delivery of this treatment by processing and storing these products.

Video thumbnail