Clinical Biotechnology Centre

The Clinical Biotechnology Centre at NHS Blood and Transplant, Filton

A video outlining the Clinical Biotechnology Centre operations at the CBC Filton facility.

The Clinical Biotechnology Centre at NHS Blood and Transplant, Filton

We have been manufacturing GMP-grade DNA plasmids for over 20 years and we now offer viral vectors (lentiviral and adeno-associated viral).

We are proud to have supported numerous clinical trials, treating patients around the world with a broad range of infectious, malignant or inherited disorders.

With a wealth of expertise and experience, we manufacture plasmids for a variety of research, pre-clinical and clinical campaigns, for healthcare, academic and commercial customers.

We have the experience to de-risk your project plans, and the know-how to overcome the challenges of transferring manufacturing processes to GMP compliance for the first time.

External image of the CBC Filton facility
Our facilities in Filton, shortly before opening in March 2023.

Images of CBC staff in clean room and laboratory spaceReasons to choose the Clinical Biotechnology Centre

  1. Our track record in small scale production of GMP-grade plasmids and proteins is second to none in the UK
  2. Our highly skilled staff draw on almost 20 years of experience
  3. We can manufacture multiple batches of plasmids concurrently on a campaign basis
  4. We draw on extensive QA and QP expertise across NHS Blood and Transplant to support the production and testing of Investigational Medicinal Products (IMPs) and the preparation of IMP Dossiers (IMPDs)
  5. We have many years’ experience importing and distributing IMPs manufactured outside of the EU
  6. We provide a bespoke service, tailored to the different needs of healthcare, academic, start-up and established gene therapy units
  7. We are an established partner of choice for the world-leading gene therapy groups across the UK and Europe

Milestones