Organ donation and transplantation

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Trials and studies in set up Trials and studies in recruitment and follow up Trials and studies in analysis Completed trials and studies

Trials and studies in set up

There are currently no trials and studies in set up under the organ donation and transplantation research theme.

Trials and studies in recruitment and follow up

DeFat

Defatting of donor transplant livers during normothermic perfusion – a randomised clinical trial.

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SIGNET

Statins for Improving Organ Outcome in Transplantation (SIGNET).

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Trials and studies in analysis

COBALT

Cardiorespiratory Optimisation By AVF Ligation After Transplantation.

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PITHIA

Pre-Implantation Trial of Histopathology In renal Allografts. A stepped-wedge cluster randomised trial.

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PLUS

Utilisation of normothermic machine preservation in extended criteria livers – a national threshold-crossing study.

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Completed trials and studies

  • EVNP: To determine if a short period of reconditioning using EVNP (Ex-vivo Normothermic Perfusion) improves initial graft function in DCD (donors after circulatory death) kidney transplantation. Visit the EVNP trial page.
  • ITOPS: A study aimed at improving transplant opportunities for patients who are sensitised. Visit the ITOPS trial page.
  • PLUTO: Plasma-Lyte Usage and assessment of kidney Transplant Outcomes in children. Visit the PLUTO trial page.
  • SONAR: A prospective observational cohort study to determine whether ultrasound surveillance can reliably predict arteriovenous fistulae (AVF) failure in patients with chronic kidney disease. Visit the SONAR trial page.

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