Publications
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Cavagnetto, C, Blanco, RA, McKenna, H, Willmott, L, Aydogdu, E, Akinyemi, N, Standring, H, Procter, S, Lagerberg, JW, Johansson, E, Croxon, H, de Korte, D, Garner, SF, Shirakami, A, Saker, J, Linssen, J, Cardigan, R. Residual red cells in blood components: A multisite study of fully automated enumeration using a hematology analyser. Transfusion. 2021 Feb;61:568-578. doi.org10.1111/trf.16196. View page on PubMed
Hervig, TA, Doughty, HA, Cardigan, RA, Apelseth, TO, Hess, JR, Noorman, F, Bohoněk, M, Yazer, MH, Lu, J, Wendel, S, Sparrow, RL. Re-introducing whole blood for transfusion: considerations for blood providers. Vox Sang. 2021 Feb;116(2):167-174. doi: 10.1111/vox.12998. View page on PubMed
Blanco, RA, Cavagnetto, C, Willmott, L, Aydogdu, E, Akinyemi, N, Standring, H, Procter, S, Garner, SF, Shirakami, A, Saker, J, Linssen, J, Cardigan, R. The use of a hematology analyzer with a new generation of software as an alternative to flow cytometry for enumerating residual white blood cells in blood components. Transfusion. 2020 Jan;60(1):155-164. doi:10.1111/trf.15606. View page on PubMed
Cardigan R, New, HV, Tinegate, H, Thomas, S. Washed red cells: theory and practice. Vox 2020 Nov;115(8):606-616. doi: 10.1111/vox.12971. View page on PubMed
Stanworth, SJ, New, HV, Apelseth, TO, Brunskill, S, Cardigan, R, Doree, C, Germain, M, Goldman, M, Massey, E, Prati, D, Shehata, N. So-Osman, C, Thachil, J. Effects of the COVID-19 pandemic on supply and use of blood for transfusion. Lancet Haematol. 2020 Oct;7(10):e756-e764. doi: 10.1016/S2352-3026(20)30186-1. View page on PubMed
Foukaneli, T, Kerr, P, Bolton-Maggs, PHB, Cardigan, R, Coles, A, Gennery, A, Jane, D, Kumaraatne, D, Manson, A, New, HV, Torpey, N and BCSH Committee. Guidelines on the use of irradiated blood components. Br. J. Haematol. 2020 Dec;191(5):704-724. doi: 10.1111/bjh.17015. View page on PubMed
Andersson, MI et al. SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus (M Munro is an author on this paper listed as MJ Robbins) Wellcome Open Res. 2020 Oct;12;5:181 doi: 10.12688/wellcomeopenres.16002.2. View page on PubMed
Shih, AW, Apelseth, TO, Cardigan, R, Marks, DC, Bégué, S, Greinacher, A, de Korte, D, Seltsam, A, Shaz, BH, Wikman, A, Barty, RL, Heddle, NM, Acker, JP. QMiP Investigators on behalf of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative. Not all red cell concentrate units are equivalent: international survey of processing and in vitro quality data. Vox Sang. 2019 Nov;114(8):783-794. doi: 10.1111/vox.12836. View page on PubMed
Smethurst, PA, Jolley, J, Braund, R, Proffitt, S, Lynes, T, Hazell, M, Mellor, P, Ridgwell, K, Procter, S, Griffiths, A, Marinaki, AM, New, HV, Murphy, GJ, Edmondson, D, Cardigan, C. Investigators on behalf of the REDJUVENATE Trial Investigators. Rejuvenation of RBCs: validation of a manufacturing method suitable for clinical use. Transfusion. 2019 Jul 11. doi: 10.1111/trf.15426. View page on PubMed
Shih AW, Apelseth TO, Cardigan R, Marks DC, Bégué S, Greinacher A, de Korte D, Seltsam A, Shaz BH, Wikman A, Barty RL, Heddle NM, Acker JP; QMiP Investigators on behalf of the Biomedical Excellence for Safer Transfusion (BEST) Collaborative. Not all red cell concentrate units are equivalent: international survey of processing and in vitro quality data. Vox Sang. 2019 Oct 22. doi: 10.1111/vox.12836. [Epub ahead of print] View page on PubMed
Huish S, Green L, Curnow E, Wiltshire M, Cardigan R. Effect of storage of plasma in the presence of red blood cells and platelets: re-evaluating the shelf life of whole blood. Transfusion. 2019 Nov;59(11):3468-3477. doi: 10.1111/trf.15549. Epub 2019 Oct 16. View page on PubMed
Platton S, Elegbe O, Bower L, Cardigan R, Lancut J, McCullagh J, Green L. Thawing times and hemostatic assessment of fresh frozen plasma thawed at 37°C and 45°C using water-bath methods. Transfusion. 2019 Nov;59(11):3478-3484. doi: 10.1111/trf.15553. Epub 2019 Oct 16. View page on PubMed
Meli A, New H, McAndrew M, Wiltshire M, R. Laboratory assessment of the quality of adult and neonatal red cell concentrates manufactured from whole blood, exchange transfusion or intrauterine transfusion red cell units. Vox Sang. 2018 May 17.Epub ahead of print. View page on PubMed
Bashir S, Meli A, Cardigan R. In vitro quality of apheresis platelets divided into paediatric-sized units and stored in PVC bags plasticised with TOTM, BTHC or DINCH. Transfus Med. 2018 Apr 11.Epub ahead of print. PubMed PMID: 29644730. View page on PubMed
Green L, Bolton-Maggs P, Beattie C, Cardigan R, Kallis Y, Stanworth SJ, Thachil J, Zahra S. British Society of Haematology Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding. Br J Haematol. 2018 Apr;181(1):54-67. Epub 2018 Mar 12. PubMed PMID: 29527654. View page on PubMed
Meli A, Hancock V, Doughty H, Smedley S, Cardigan R, Wiltshire M. Investigation of the quality of stored red blood cells after simulated air drop in the maritime environment. Transfusion. 2018 Feb;58(2):423-429. Epub 2017 Nov 27. PubMed PMID: 29193159. View page on PubMed
Woźniak MJ, Qureshi S, Sullo N, Dott W, Cardigan R, Wiltshire M, Nath M, Patel NN, Kumar T, Goodall AH, Murphy GJ. A Comparison of Red Cell Rejuvenation versus Mechanical Washing for the Prevention of Transfusion-associated Organ Injury in Swine. Anesthesiology. 2018 Feb;128(2):375-385. PubMed PMID: 29120945. View page on PubMed
Kelly AM, Garner SF, Foukaneli T, Godec TR, Herbert N, Kahan BC, Deary A, Bakrania L, Llewelyn C, Ouwehand WH, Williamson LM, Cardigan RA. The effect of variation in donor platelet function on transfusion outcome: a semirandomized controlled trial. Blood. 2017 Jul 13;130(2):214-220. Epub 2017 May 9. PubMed PMID: 28487294. View page on PubMed
Wozniak MJ, Sullo N, Qureshi S, Dott W, Cardigan R, Wiltshire M, Morris T, Nath M, Bittar N, Bhudia SK, Kumar T, Goodall AH, Murphy GJ. Randomized trial of red cell washing for the prevention of transfusion-associated organ injury in cardiac surgery. Br J Anaesth. 2017 May 1;118(5):689-698. PubMed PMID: 28475670; PubMed Central PMCID: PMC5430295. View page on PubMed
Germain M, Grégoire Y, Vassallo RR, Acker JP, Cardigan R, de Korte D, Irving DO, Bégué S; Biomedical Excellence for Safer Transfusions (BEST) collaborative. Quality control of apheresis platelets: a multicentre study to evaluate factors that can influence pH measurement. Vox Sang. 2017 May;112(4):318-325. Epub 2017 Mar 23. PubMed PMID: 28337765. View page on PubMed
Garner SF, Furnell A, Kahan BC, Jones CI, Attwood A, Harrison P, Kelly AM, Goodall AH, Cardigan R, Ouwehand WH. Platelet responses to agonists in a cohort of highly characterised platelet donors are consistent over time. Vox Sang. 2017 Jan;112(1):18-24. Epub 2016 Dec 21. PubMed PMID: 28001309; PubMed Central PMCID: PMC5299478. View page on PubMed
Backholer L, Green L, Huish S, Platton S, Wiltshire M, Doughty H, Curnow E, Cardigan R. A paired comparison of thawed and liquid plasma. Transfusion. 2017 Apr;57(4):881-889. Epub 2016 Nov 23. PubMed PMID: 27882572. View page on PubMed
Green L, Cardigan R, Beattie C, Bolton-Maggs P, Stanworth SJ, Thachil J, Kallis Y, Zahra S. Addendum to the British Committee for Standards in Haematology (BCSH): Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant, 2004 (Br. J Haematol 2004,126,11-28). Br J Haematol. 2017 Aug;178(4):646-647. Epub 2016 Jun 16. PubMed PMID: 27306832. View page on PubMed
Green L, Backholer L, Wiltshire M, Platton S, Stanworth SJ, Cardigan R. The hemostatic properties of thawed pooled cryoprecipitate up to 72 hours. Transfusion. 2016 Jun;56(6):1356-61. Epub 2016 Mar 28. PubMed PMID: 27019386. View page on PubMed
Wiltshire M, Meli A, Schott MA, Erickson A, Mufti N, Thomas S, Cardigan R. Quality of red cells after combination of prion reduction and treatment with the intercept system for pathogen inactivation. Transfus Med. 2016 Jun;26(3):208-14. Epub 2016 Mar 23. PubMed PMID: 27006102. View page on PubMed
Backholer L, Wiltshire M, Proffitt S, Cookson P, Cardigan R. Paired comparison of methylene blue- and amotosalen-treated plasma and cryoprecipitate. Vox Sang. 2016 May;110(4):352-61. Epub 2016 Jan 12. PubMed PMID: 26757252. View page on PubMed
Hubbard T, Backholer L, Wiltshire M, Cardigan R, Ariëns RA. Effects of riboflavin and amotosalen photoactivation systems for pathogen inactivation of fresh-frozen plasma on fibrin clot structure. Transfusion. 2016 Jan;56(1):41-8. Epub 2015 Sep 10. PubMed PMID: 26358662. View page on PubMed
Proffitt S, Thomas S, Swann I, Popovsky MA, Smith DJ, Roberts DJ, Cardigan R. Storage of washed or irradiated red cells in AS-7 improves their in vitro characteristics. Vox Sang. 2015 Oct;109(3):203-13. Epub 2015 Apr 20. PubMed PMID: 25900147. View page on PubMed
Cardigan R, Green L. Thawed and liquid plasma--what do we know? Vox Sang. 2015 Jul;109(1):1-10. Epub 2015 Mar 31. Review. PubMed PMID: 25833464. View page on PubMed
Green L, Allard S, Cardigan R. Modern banking, collection, compatibility testing and storage of blood and blood components. Anaesthesia. 2015 Mar;70(3):373. PubMed PMID: 28339099. View page on PubMed
Cookson P, Lawrie A, Green L, Dent E, Proffitt S, Bashir S, Thomas S, Cardigan R. Thrombin generation and coagulation factor content of thawed plasma and platelet concentrates. Vox Sang. 2015 Feb;108(2):160-8. Epub 2014 Dec 3. PubMed PMID: 25469449. View page on PubMed
Green L, Allard S, Cardigan R. Modern banking, collection, compatibility testing and storage of blood and blood components. Anaesthesia. 2015 Jan;70 Suppl 1:3-9, e2. Review. Erratum in: Anaesthesia. 2015 Mar;70(3):373. Anaesthesia. 2015 Mar;70(3):373. PubMed PMID: 25440389. View page on PubMed
Bawazir WM, Flatt JF, Wallis JP, Rendon A, Cardigan RA, New HV, Wiltshire M, Page L, Chapman CE, Stewart GW, Bruce LJ. Familial pseudohyperkalemia in blood donors: a novel mutation with implications for transfusion practice. Transfusion. 2014 Dec;54(12):3043-50. Epub 2014 Jun 19. PubMed PMID: 24947683. View page on PubMed
Aston A, Cardigan R, Bashir S, Proffitt S, New H, Brown C, Liesner R, Hennem S, Nulty H, Shaw O, Vaughan R, Kim JJ, Rees L. Washing red cells after leucodepletion does not decrease human leukocyte antigen sensitization risk in patients with chronic kidney disease. Pediatr Nephrol. 2014 Oct;29(10):2005-11. Epub 2014 Apr 29. PubMed PMID: 24777534. View page on PubMed
Nightingale MJ, Brazier AM, McArthur K, Jones J, Cardigan R, Lodge L, Maclennan S; UK Blood Services Blood Component Label Steering and Work Groups. The development and evaluation of options for improving future U.K. blood component labelling--outcome of the 2013 U.K. hospital survey. Transfus Med. 2014 Apr;24(2):89-98. Epub 2014 Jan 11. PubMed PMID: 24410716. View page on PubMed
van der Meer PF, Reesink HW, Panzer S, Wong J, Ismay S, Keller A, Pink J, Buchta C, Compernolle V, Wendel S, Biagini S, Scuracchio P, Thibault L, Germain M, Georgsen J, Bégué S, Dernis D, Raspollini E, Villa S, Rebulla P, Takanashi M, de Korte D, Lozano M, Cid J, Gulliksson H, Cardigan R, Tooke C, Fung MK, Luban NL, Vassallo R, Benjamin R. Should DEHP be eliminated in blood bags? Vox Sang. 2014 Feb;106(2):176-95. Epub 2013 Dec 12. PubMed PMID: 24330039. View page on PubMed
Bashir S, Nightingale MJ, Cardigan R. Ensuring that blood transfusion sets administer an effective dose of functional blood components. Transfus Med. 2013 Aug;23(4):226-30. Epub 2013 May 14. PubMed PMID: 23668816. View page on PubMed
Bashir S, Wiltshire M, Cardigan R, Thomas S. Lipaemic plasma induces haemolysis in resuspended red cell concentrate. Vox Sang. 2013 Apr;104(3):218-24. Epub 2012 Oct 25. PubMed PMID: 23106259. View page on PubMed
Thomas S, Hancock V, Cardigan R. The 30 minute rule for red blood cells: in vitro quality assessment after repeated exposure to 30°C. Transfusion. 2013 Jun;53(6):1169-77. Epub 2012 Sep 21. PubMed PMID: 22995049. View page on PubMed
Bashir S, Cookson P, Wiltshire M, Hawkins L, Sonoda L, Thomas S, Seltsam A, Tolksdorf F, Williamson LM, Cardigan R. Pathogen inactivation of platelets using ultraviolet C light: effect on in vitro function and recovery and survival of platelets. Transfusion. 2013 May;53(5):990-1000. Epub 2012 Aug 21. PubMed PMID: 22905813. View page on PubMed
Thomas S, Hancock V, Cardigan R. Repeated short-term warming of red blood cell concentrates has minimal effect on their quality. Vox Sang. 2012 Aug;103(2):113-21. Epub 2012 Mar 10. PubMed PMID: 22404883. View page on PubMed
Brunskill S, Thomas S, Whitmore E, McDonald CP, Dorée C, Hopewell S, Staves J, Cardigan R, Murphy MF. What is the maximum time that a unit of red blood cells can be safely left out of controlled temperature storage? Transfus Med Rev. 2012 Jul;26(3):209-223.e3. Epub 2011 Nov 25. Review. PubMed PMID: 22119493. View page on PubMed
Cookson P, Thomas S, Marschner S, Goodrich R, Cardigan R. In vitro quality of single-donor platelets treated with riboflavin and ultraviolet light and stored in platelet storage medium for up to 8 days. Transfusion. 2012 May;52(5):983-94. Epub 2011 Oct 20. PubMed PMID: 22014032. View page on PubMed
Cardigan R, Themessl A, Garwood M. Short-term deviations in temperature during storage of plasma at -40°C do not affect its quality. Transfusion. 2011 Jul;51(7):1541-5. Epub 2011 Jan 28. PubMed PMID: 21736574. View page on PubMed
Hancock V, Cardigan R, Thomas S. Red cell concentrate storage and transport temperature. Transfus Med. 2011 Oct;21(5):325-9. Epub 2011 Jun 26. PubMed PMID: 21707796. View page on PubMed
Bashir S, Naik F, Cardigan R, Thomas S. Effect of X-irradiation on the quality of red cell concentrates. Vox Sang. 2011 Oct;101(3):200-7. 2011 Apr 15. PubMed PMID: 21492185. View page on PubMed
Beard MJ, Jeewa Z, Bashir S, Cardigan R, Thomas S. Comparison of platelet activation in platelet concentrates measured by flow cytometry or ADVIA 2120. Vox Sang. 2011 Aug;101(2):122-30. Epub 2011 Apr 15. PubMed PMID: 21492182. View page on PubMed
Thomas S, Wiltshire M, Hancock V, Fletcher S, McDonald C, Cardigan R. Core temperature changes in red blood cells. Transfusion. 2011 Feb;51(2):442-3. PubMed PMID: 21309781. View page on PubMed
Cardigan R, Van der Meer PF, Pergande C, Cookson P, Baumann-Baretti B, Cancelas JA, Devine D, Gulliksson H, Vassallo R, de Wildt-Eggen J. Coagulation factor content of plasma produced from whole blood stored for 24 hours at ambient temperature: results from an international multicenter BEST Collaborative study. Transfusion. 2011 Jan;51 Suppl 1:50S-57S. PubMed PMID: 21223296.
View page on PubMed
Dijkstra-Tiekstra MJ, van der Meer PF, Cardigan R, Devine D, Prowse C, Sandgren P, de Wildt-Eggen J; Biomedical Excellence for Safer Transfusion Collaborative. Platelet concentrates from fresh or overnight-stored blood, an international study. Transfusion. 2011 Jan;51 Suppl 1:38S-44S. PMID: 21223294. View page on PubMed
van der Meer PF, Cancelas JA, Cardigan R, Devine DV, Gulliksson H, Sparrow RL, Vassallo RR, de Wildt-Eggen J, Baumann-Baretti B, Hess JR; BEST Collaborative. Evaluation of overnight hold of whole blood at room temperature before component processing: effect of red blood cell (RBC) additive solutions on in vitro RBC measures. Transfusion. 2011 Jan;51 Suppl 1:15S-24S.. PubMed PMID: 21223291. View page on PubMed
Cookson P, Sutherland J, Turner C, Bashir S, Wiltshire M, Hancock V, Smith K, Cardigan R. Platelet apoptosis and activation in platelet concentrates stored for up to 12 days in plasma or additive solution. Transfus Med. 2010 Dec;20(6):392-402. Epub 2010 Aug 26. PubMed PMID: 20738829. View page on PubMed
Wiltshire M, Cardigan R, Thomas S. Manufacture of red cells in additive solution from whole blood refrigerated for 5 days or remanufactured from red cells stored in plasma. Transfus Med. 2010 Dec;20(6):383-91. PubMed PMID: 20681977. View page on PubMed
Thomas S, Bekoe Y, Uddin S, Beard M, Cardigan R. Double red cell concentrates -in vitro quality after delayed refrigeration. Transfus Med. 2010 Oct;20(5):315-21. PubMed PMID: 20456686. View page on PubMed
Reesink HW, Panzer S, McQuilten ZK, Wood EM, Marks DC, Wendel S, Trigo F, Biagini S, Olyntho S, Devine DV, Mumford I, Cazenave JP, Rasonglès P, Garraud O, Richard P, Schooneman F, Vezon G, Al Radwan R, Brand A, Hervig T, Castro E, Lozano M, Navarro L, Puig L, Almazán C, MacLennan S, Cardigan R, Franklin IM, Prowse C. Pathogen inactivation of platelet concentrates. Vox Sang. 2010 Jul 1;99(1):85-95. Epub 2010 Mar 10. PubMed PMID: 20230599. View page on PubMed
Hess JR, Sparrow RL, van der Meer PF, Acker JP, Cardigan RA, Devine DV. Red blood cell hemolysis during blood bank storage: using national quality management data to answer basic scientific questions. Transfusion. 2009 Dec;49(12):2599-603. PubMed PMID: 20163690. View page on PubMed
Wiltshire M, Thomas S, Scott J, Hicks V, Haines M, Cookson P, Garwood M, Cardigan R. Prion reduction of red blood cells: impact on component quality. Transfusion. 2010 May;50(5):970-9. Epub 2009 Nov 23. PubMed PMID: 19951322. View page on PubMed
Thomas S, Beard M, Garwood M, Callaert M, Cardigan R. Platelet concentrates produced from whole blood using the Atreus processing system. Vox Sang. 2009 Aug;97(2):93-101. Epub 2009 Apr 9. PubMed PMID: 19392785. View page on PubMed
Forsythe J, Cardigan R. Advisory committee on the safety of blood, tissues and organs. Transfus Med. 2009 Apr;19(2):57-8. Epub 2009 Mar 23. PubMed PMID: 19320856. View page on PubMed
Lawrie AS, Albanyan A, Cardigan RA, Mackie IJ, Harrison P. Microparticle sizing by dynamic light scattering in fresh-frozen plasma. Vox Sang. 2009 Apr;96(3):206-12. Epub 2009 Jan 19. PubMed PMID: 19175566. View page on PubMed
Cardigan R, Philpot K, Cookson P, Luddington R. Thrombin generation and clot formation in methylene blue-treated plasma and cryoprecipitate. Transfusion. 2009 Apr;49(4):696-703. Epub 2009 Jan 5. PubMed PMID: 19170989. View page on PubMed
Lawrie AS, Harrison P, Cardigan RA, Mackie IJ. The characterization and impact of microparticles on haemostasis within fresh-frozen plasma. Vox Sang. 2008 Oct;95(3):197-204. PubMed PMID: 19121184. View page on PubMed
Thomas S, Beard M, Garwood M, Callaert M, Waeg Gv, Cardigan R. Blood components produced from whole blood using the Atreus processing system. Transfusion. 2008 Dec;48(12):2515-24. Epub 2008 Sep 4. PubMed PMID: 18774965. View page on PubMed
Wilsher C, Garwood M, Sutherland J, Turner C, Cardigan R. The effect of storing whole blood at 22 degrees C for up to 24 hours with and without rapid cooling on the quality of red cell concentrates and fresh-frozen plasma. Transfusion. 2008 Nov;48(11):2338-47. Epub 2008 Jul 22. PubMed PMID: 18657079. View page on PubMed
Bashir S, Stanworth S, Massey E, Goddard F, Cardigan R. Neutrophil function is preserved in a pooled granulocyte component prepared from whole blood donations. Br J Haematol. 2008 Mar;140(6):701-11. PubMed PMID: 18302716. View page on PubMed
Lawrie AS, Cardigan RA, Williamson LM, Machin SJ, Mackie IJ. The dynamics of clot formation in fresh-frozen plasma. Vox Sang. 2008 May;94(4):306-14. Epub 2008 Feb 5. PubMed PMID: 18266780. View page on PubMed
Cardigan R, Sutherland J, Garwood M, Bashir S, Turner C, Smith K, Hancock V, Wiltshire M, Pergande C, Williamson LM. In vitro function of buffy coat-derived platelet concentrates stored for 9 days in CompoSol, PASII or 100% plasma in three different storage bags. Vox Sang. 2008 Feb;94(2):103-12. Epub 2007 Nov 22. PubMed PMID: 18034786. View page on pubMed
Cardigan R, Lawrie AS, Mackie IJ, Williamson LM. The quality of fresh-frozen plasma produced from whole blood stored at 4 degrees C overnight. Transfusion. 2005 Aug;45(8):1342-8. PubMed PMID: 16078924. View page on PubMed
Hess JR, Kagen LR, van der Meer PF, Simon T, Cardigan R, Greenwalt TJ, AuBuchon JP, Brand A, Lockwood W, Zanella A, Adamson J, Snyder E, Taylor HL, Moroff G, Hogman C. Interlaboratory comparison of red-cell ATP, 2,3-diphosphoglycerate and haemolysis measurements. Vox Sang. 2005 Jul;89(1):44-8. PubMed PMID: 15938739. View page on PubMed
Turner CP, Sutherland J, Wadhwa M, Dilger P, Cardigan R. In vitro function of platelet concentrates prepared after filtration of whole blood or buffy coat pools. Vox Sang. 2005 Apr;88(3):164-71. PubMed PMID: 15787726. View page on PubMed
Cardigan R, Turner C, Harrison P. Current methods of assessing platelet function: relevance to transfusion medicine. Vox Sang. 2005 Apr;88(3):153-63. Review. PubMed PMID: 15787725. View page on PubMed
Cookson P, Sutherland J, Cardigan R. A simple spectrophotometric method for the quantification of residual haemoglobin in platelet concentrates. Vox Sang. 2004 Nov;87(4):264-71. PubMed PMID: 15585022. View page on PubMed
Beard MJ, Cardigan R, Seghatchian J, Krailadsiri P, Williamson LM. Variables determining blockage of WBC-depleting filters by Hb sickle cell trait donations. Transfusion. 2004 Mar;44(3):422-30. PubMed PMID: 14996202. View page on PubMed
Bashir S, Cardigan R. Granulocyte concentrates: how can we assess their quality? Transfus Med. 2003 Oct;13(5):245-57. Review. PubMed PMID: 14617335.
https://www.ncbi.nlm.nih.gov/pubmed/?term=14617335
Gulliksson H, AuBuchon JP, Cardigan R, van der Meer PF, Murphy S, Prowse C, Richter E, Ringwald J, Smacchia C, Slichter S, de Wildt-Eggen J. Storage of platelets in additive solutions: a multicentre study of the in vitro effects of potassium and magnesium. Vox Sang. 2003 Oct;85(3):199-205. PubMed PMID: 14516450.
https://www.ncbi.nlm.nih.gov/pubmed/?term=14516450
Bashir S, Cardigan R. The origin and identification of unknown events associated with low-level leucocyte counting by flow cytometry. Vox Sang. 2003 Oct;85(3):190-8. PubMed PMID: 14516449. https://www.ncbi.nlm.nih.gov/pubmed/?term=14516449
Williamson LM, Cardigan R, Prowse CV. Methylene blue-treated fresh-frozen plasma: what is its contribution to blood safety? Transfusion. 2003 Sep;43(9):1322-9. Review. PubMed PMID: 12919437. https://www.ncbi.nlm.nih.gov/pubmed/?term=12919437
Garwood M, Cardigan RA, Drummond O, Hornsey VS, Turner CP, Young D, Williamson LM, Prowse CV. The effect of methylene blue photoinactivation and methylene blue removal on the quality of fresh-frozen plasma. Transfusion. 2003 Sep;43(9):1238-47. PubMed PMID: 12919426. https://www.ncbi.nlm.nih.gov/pubmed/?term=12919426
Cardigan R, Williamson LM. The quality of platelets after storage for 7 days. Transfus Med. 2003 Aug;13(4):173-87. Review. PubMed PMID: 12880388.
https://www.ncbi.nlm.nih.gov/pubmed/?term=12880388
Cardigan R, Sutherland J, Wadhwa M, Dilger P, Thorpe R. The influence of platelet additive solutions on cytokine levels and complement activation in platelet concentrates during storage. Vox Sang. 2003 Jan;84(1):28-35. PubMed PMID: 12542731.
https://www.ncbi.nlm.nih.gov/pubmed/?term=12542731
Beckman N, Cardigan R, Wallington T, Williamson LM. Value of central analysis of leucocyte depletion quality control data within the National Blood Service, England. Vox Sang. 2002 Aug;83(2):110-8. PubMed PMID: 12201840. View page on PubMed
Cardigan R, Phipps A, Seghatchian J, Bashir S, Aynsley S, Beckman N, Barnett D, Reilly JT, Williamson LM. The development of a national standardized approach for the enumeration of residual leucocytes in blood components. Vox Sang. 2002 Aug;83(2):100-9. PubMed PMID: 12201839. View page on PubMed
Cardigan R, Allford S, Williamson L. Levels of von Willebrand factor-cleaving protease are normal in methylene blue-treated fresh-frozen plasma. Br J Haematol. 2002 Apr;117(1):253-4. PubMed PMID: 11918568. View page on PubMed
Cardigan R, Smith K. Evaluation of the HemoCue plasma haemoglobin analyser for assessing haemolysis in red cell concentrates during storage. Vox Sang. 2002 Feb;82(2):76-9. PubMed PMID: 11906671. View page on PubMed
Adams MJ, Cardigan RA, Marchant WA, Grocott MP, Mythen MG, Mutch M, Purdy G, Mackie IJ, Machin SJ. Tissue factor pathway inhibitor antigen and activity in 96 patients receiving heparin for cardiopulmonary bypass. J Cardiothorac Vasc Anesth. 2002 Feb;16(1):59-63. PubMed PMID: 11854880. View page on PubMed
Cardigan R, Sutherland J, Garwood M, Krailadsiri P, Seghatchian J, Beard M, Beckman N, Williamson LM. The effect of leucocyte depletion on the quality of fresh-frozen plasma. Br J Haematol. 2001 Jul;114(1):233-40. PubMed PMID: 11472374. View page on PubMed
Cardigan RA, Crook M, Mackie IJ, Machin SJ. Plasma levels of factor XIIa and factor VIIa are increased but not related in primary hyperlipidaemia. Blood Coagul Fibrinolysis. 2001 Apr;12(3):187-92. PubMed PMID: 11414632. View page on PubMed
Royston D, Cardigan R, Gippner-Steppert C, Jochum M. Is perioperative plasma aprotinin concentration more predictable and constant after a weight-related dose regimen? Anesth Analg. 2001 Apr;92(4):830-6. PubMed PMID: 11273910. View page on PubMed
Cardigan RA, Mackie IJ, Gippner-Steppert C, Jochum M, Royston D, Gallimore MJ. Determination of plasma aprotinin levels by functional and immunologic assays. Blood Coagul Fibrinolysis. 2001 Jan;12(1):37-42. PubMed PMID: 11229825. View page on PubMed
Beard MJ, Seghatchian J, Cardigan R, Bennett J, Smith KM, Williamson L. Leucofiltration of sickle cell trait blood "the blocker": NBS London & S.E. experience. Transfus Sci. 2000 Feb-Apr;22(1-2):71-3. PubMed PMID: 10771388. View page on PubMed
Cardigan RA, McGloin H, Mackie IJ, Machin SJ, Singer M. Activation of the tissue factor pathway occurs during continuous venovenous hemofiltration. Kidney Int. 1999 Apr;55(4):1568-74. PubMed PMID: 10201024. View page on PubMed
Cardigan R, McGloin H, Mackie I, Machin S, Singer M. Endothelial dysfunction in critically ill patients: the effect of haemofiltration. Intensive Care Med. 1998 Dec;24(12):1264-71. PubMed PMID: 9885878. View page on PubMed
Cardigan RA, Donohoe S, Purdy G, Mackie IJ, Machin SJ. The association of factor VIIa, factor XIIa and beta2-glycoprotein-1 with triglyceride-rich lipoproteins in normolipidaemic subjects. Blood Coagul Fibrinolysis. 1998 Jun;9(4):323-32. PubMed PMID: 9690803. View page on PubMed
Hamilton-Davies C, Barclay GR, Cardigan RA, McDonald SJ, Purdy G, Machin SJ, Webb AR. Relationship between preoperative endotoxin immune status, gut perfusion, and outcome from cardiac valve replacement surgery. Chest. 1997 Nov 5;112(5):1189-96. PubMed PMID: 9367456. View page on PubMed
Cardigan RA, Mackie IJ, Machin SJ. Hemostatic-endothelial interactions: a potential anticoagulant role of the endothelium in the pulmonary circulation during cardiac surgery. J Cardiothorac Vasc Anesth. 1997 May;11(3):329-36. Review. PubMed PMID: 9161902. View page on PubMed
Salmon J, Cardigan R, Mackie I, Cohen SL, Machin S, Singer M. Continuous venovenous haemofiltration using polyacrylonitrile filters does not activate contact system and intrinsic coagulation pathways. Intensive Care Med. 1997 Jan;23(1):38-43. PubMed PMID: 9037638. View page on PubMed
Harrison P, Cardigan R, Harrison C, Addison I, Chavda N, Chitolie A, Machin SJ. Delayed effect of desmopressin on circulating neutrophils and monocytes. Br J Haematol. 1996 Dec;95(3):570-1. PubMed PMID: 8943904. View page on PubMed
Bennett-Guerrero E, Sorohan JG, Howell ST, Ayuso L, Cardigan RA, Newman MF, Mackie IJ, Reves JG, Mythen MG. Maintenance of therapeutic plasma aprotinin levels during prolonged cardiopulmonary bypass using a large-dose regimen. Anesth Analg. 1996 Dec;83(6):1189-92. PubMed PMID: 8942584. View page on PubMed
Cardigan RA, Mackie IJ, Machin SJ. The effect of heparin and its neutralisation on functional assays for factor VIIa, factor VII and TFPI. Thromb Res. 1996 Nov 15;84(4):237-42. PubMed PMID: 8948048. View page on PubMed
Cardigan RA, Hamilton-Davies C, McDonald S, Purdy G, Mackie IJ, Webb AR, Machin SJ. Haemostatic changes in the pulmonary blood during cardiopulmonary bypass. Blood Coagul Fibrinolysis. 1996 Jul;7(5):567-77. PubMed PMID: 8874868. View page on PubMed