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Convalescent plasma programme

As part of the national research effort against coronavirus, NHSBT are currently collecting plasma from recovered COVID-19 patients to help with national clinical trials.

Find out more about the convalescent plasma trials and other COVID-19 related research

About us

About the Clinical Biotechnology Centre

The Clinical Biotechnology Centre was opened in April 1999. Our aim is to be the preferred provider of quality-assured DNA and protein-based therapeutics for healthcare, academic and commercial customers seeking to establish the safety and efficacy of innovative cellular and molecular therapies.

We manufacture small scale batches of GMP-grade plasmids. These are small fragments of DNA, used to carry a gene of interest into human cells. Each batch is characteristically unique and tailored to the specific requirements of each customer.

Over the past decade, we have been proud to support numerous high profile clinical trials, treating patients around the world with a broad range of infectious, malignant or inherited disorders.

We were thrilled to be awarded Leading Gene Therapy Products Manufacturer in the UK (2016), and Best Clinical Biotechnology Research Facility in the UK (2017).

Our milestones

The centre opened
The centre opened
The centre opened
The centre became fully operational
The centre opened

First recombinant monoclonal antibody released for clinical trial

First plasmid DNA released for clinical trial
The centre opened

Multiple humanised monoclonal antibody trials started

Production of 30-40 bespoke patient specific plasmid DNA vaccinations started
The centre opened
First publicly-funded facility to be receive MHRA Manufacturing Authorisation
The centre opened
Successful MHRA re-inspection, with licence extended to include importation of Investigational Medicinal Products
The centre opened

Collaborator on £1.2million EME NIHR Grant

Successful MHRA re-inspection
The centre opened
Strategic partnership with UCL Gene Therapy Consortium
The centre opened
Successful MHRA re-inspection
The centre opened
Awarded Leading Gene Therapy Products Manufacturer in the UK
The centre opened
Awarded Best Clinical Biotechnology Research Facility in the UK Concept design completed for new facility at NHSBT, Filton

Get in touch

Call us on:

01934 880 150

07471 147 804

Email us at:


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