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REDDS

Title
Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes. A pilot, feasibility study.
Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes. A pilot, feasibility study.
Study Type
Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes. A pilot, feasibility study.
Randomised controlled trial
Chief Investigator(s)
Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes. A pilot, feasibility study.
Dr Simon Stanworth and Professor David Bowen
Primary Sponsor
Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes. A pilot, feasibility study.
NHSBT
Funder
Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes. A pilot, feasibility study.
NHSBT Trust Fund Grant
NHSBT Research Theme
Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes. A pilot, feasibility study.
Patient Blood Management
Summary
Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes. A pilot, feasibility study.

Red blood cell transfusion thresholds and Quality of Life in myelodysplastic syndromes (MDS). A pilot, feasibility study.

The ultimate goal of this feasibility trial is to inform the design for a large randomised controlled trial to compare a restrictive (transfuse to maintain haemoglobin concentration between 85 and 100g/L) with a liberal (transfuse to maintain haemoglobin concentration between 110-125g/L) red cell transfusion strategy for clinical outcomes.

Study Hypothesis
Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes. A pilot, feasibility study.
A randomised controlled feasibility trial to evaluate protocol adherence between a restrictive (transfuse to maintain haemoglobin concentration between 85 and 100g/L) and a liberal (transfuse to maintain haemoglobin concentration between 110-125g/L) red cell transfusion strategy.
Study Contact
Red blood cell transfusion thresholds and QoL in myelodysplastic syndromes. A pilot, feasibility study.

Heather Smethurst

Email: heather.smethurst@nhsbt.nhs.uk

Tel: 07471 177896