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ProGrES

Title
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.
Study Type
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.
Observational study
Chief Investigator(s)
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.
Dr Suzy Morton
Primary Sponsor
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.
N/A
Funder
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.
N/A
NHSBT Research Theme
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.
Patient Blood Management
Summary
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.
Granulocyte transfusions may be considered for transfusion to patients with refractory infection who have quantitative or qualitative deficiencies in their own neutrophils.
Study Hypothesis
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.
The study will help to understand how granulocytes are being used in the UK. This includes patient demographics, underlying conditions and treatment received, e.g. type of leukaemia, chemotherapy treatment, concomitant treatment for infection, indication for transfusion, dose and schedule, and outcomes.
Study Design
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.

The protocol describes a prospective study of outcomes following transfusion of granulocytes in the UK. To collect information on indications, dose and outcomes following use of granulocytes administered to children and adults.

Information will be collected on patients in UK hospitals receiving pooled granulocytes (issued by NHSBT) or directed donations collected by apheresis (issued by King’s College Hospital London).

Study Contact
ProGrES: A prospective granulocyte usage and outcomes survey.
An observational study.

Charlotte Brierley

Email: charlotte.brierley1@nhs.net

Emma Laing

Email: emma.laing@nhsbt.nhs.uk