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PITHIA

Title
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts
Study Type
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts
Stepped-wedge cluster randomised trial
Chief Investigator(s)
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts
Mr Gavin Pettigrew
Primary Sponsor
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts
Cambridge University Hospitals
Funder
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts
NIHR Research for Patient benefit
NHSBT Research Theme
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts
Organ Donation and Transplantation
Summary
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts
Does the introduction of a national, pre-implantation biopsy histopathology service increase numbers and improve outcomes of kidney transplants performed in the UK?
Study Hypothesis
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts

Provision of a national, 24/7 pre-implantation biopsy service results - at reasonable cost - in the transplantation of a greater proportion of kidneys offered from ECD donors, and/or improves kidney transplant function at one year post-transplant.

Numbers of deceased donor kidney transplants performed annually in the UK are consequently significantly increased or improved in quality.

Study Design
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts
An open, stepped-wedge cluster, randomised trial.
Study Contact
PITHIA: Pre-Implantation trial of Histopathology in renal Allografts

Emma Laing

Email: emma.laing@nhsbt.nhs.uk

Tel: 07471 147868