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ATHENA

PLEASE NOTE: This study is now complete.

Title
ATHENA
ATHENA
Study Type
ATHENA
Pilot study
Chief Investigator(s)
ATHENA
Lise Estcourt
Primary sponsor
ATHENA
NHSBT
Funder
ATHENA
NHSBT
Summary
ATHENA
Risk Factors for haemorrhage in thrombocytopenic haematology patients. A pilot clinical investigation.
Study Hypothesis
ATHENA

This pilot study will aim to examine a small number of patients in careful detail to document the key abnormalities in coagulation.

This is a preliminary study, and if a association is seen between coagulation abnormalities and bleeding this will guide the development of future studies.

Study Design
ATHENA
The design is a prospective, observational cohort study which will follow the clinical course of patients admitted with a haematological malignancy that requires intensive chemotherapy or a stem cell transplant. Up to 50 patients will be recruited to the study.
Publications
ATHENA
Estcourt LJ, Stanworth SJ, Harrison P, Powter G, McClure M, Murphy M, Mumford AD. Prospective observational cohort study of the association between thromboelastometry, coagulation and platelet parameters and bleeding in patients with haematoogical malignancies – The ATHENA study. British Journal of Haematology. [E Pub 05 May 2014 doi: 10.1111/bjh.12928].